SnapShot: Spliceosome Dynamics II

نویسندگان

  • Markus C. Wahl
  • Reinhard Lührmann
چکیده

Numerous mechanisms exploit or modulate the conformational/compositional dynamics of spliceosomes to regulate splicing. The majority of higher eukaryotic protein-coding genes contain more than one intron and the derived pre-mRNAs can be alternatively spliced. Diverse principles ensure the reliable identification of authentic splice sites while concomitantly providing flexibility in splice site choice during alternative splicing. Some species contain a second type of minor (U12-type) spliceosome.

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عنوان ژورنال:
  • Cell

دوره 162  شماره 

صفحات  -

تاریخ انتشار 2015